Detection of Lysergic Acid Diethylamide (LSD) in Urine by Gas Chromatography-Ion Trap Tandem Mass Spectrometry
نویسندگان
چکیده
منابع مشابه
Radioimmunoassay of lysergic acid diethylamide (LSD) in serum and urine by using antisera of different specificities.
We raised high-titre antisera to two LSD-bovine serum albumin conjugates, one linked via the indole nitrogen, the other via the amide side-chain. The antisera were specific for different parts of the LSD molecule, as demonstrated by cross-reactivity studies with LSD, its metabolites, ergot alkoloids, and closely related compounds. The antisera were used to develop a double-antibody radioimmunoa...
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In all, 3872 urine specimens were screened for lysergic acid diethylamide (LSD) using the CEDIA DAU LSD assay. Forty-eight samples, mainly from psychiatric patients or drug abusers, were found to be LSD positive, but only 13 (27%) of these could be confirmed by high-performance liquid chromatography with fluorescence detection (HPLC-FLD) following immunoaffinity extraction (IAE). Additional ana...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 1999
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/23.6.474